Detected molecules : Enantiomers of Baclofen
Separation device : CE
Excitation wavelength : 442
Dye : NDA
This application note describes the separation of Enantioseparation of Baclofen by Capillary Electrophoresis with Laser-Induced Fluorescence Detection. Baclofen (Lioresal®) is a GABA (gamma-aminobutyric acid) agonist, a neurotransmitter inhibitor. It is habitually prescribed in the treatment of spasticity. It also shows some efficacy in neuralgia of the triplet and in some neuropathic attacks. It is sometimes useful in paroxysmic pains not relieved by antiepileptics.